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<th valign="baseline" align="right" nowrap="">Subject: </th>
<td>[evol-psych] 'Maternal' DNA Can Be Inherited from Dad, Too</td>
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<th valign="baseline" align="right" nowrap="">Date: </th>
<td>Thu, 22 Aug 2002 18:01:06 -0600</td>
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<th valign="baseline" align="right" nowrap="">From: </th>
<td>Ian Pitchford <a class="moz-txt-link-rfc2396E" href="mailto:ian.pitchford@scientist.com"><ian.pitchford@scientist.com></a></td>
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<th valign="baseline" align="right" nowrap="">Reply-To: </th>
<td>Ian Pitchford <a class="moz-txt-link-rfc2396E" href="mailto:ian.pitchford@scientist.com"><ian.pitchford@scientist.com></a></td>
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<th valign="baseline" align="right" nowrap="">Organization: </th>
<td><a class="moz-txt-link-freetext" href="http://human-nature.com/">http://human-nature.com/</a></td>
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<th valign="baseline" align="right" nowrap="">To: </th>
<td><a class="moz-txt-link-abbreviated" href="mailto:evolutionary-psychology@yahoogroups.com">evolutionary-psychology@yahoogroups.com</a></td>
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<div class="storyheadline"><font face="Arial">'Maternal' DNA Can Be Inherited
from Dad, Too</font></div>
<!-- Yahoo TimeStamp: 1029966182 -->
<div class="timedate"><font face="Arial">Wed Aug 21, 5:43 PM ET</font></div>
<p><!-- TextStart --><font face="Arial"><font size="-1"><i>By Linda Carroll</i></font>
</font></p>
<p><font face="Arial">NEW YORK (Reuters Health) - Tiny bits of DNA that scientists
thought could only come from a child's mother may sometimes also come from
the father, a new study shows. </font></p>
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<p><font face="Arial">Usually, mammals inherit mitochondria--small structures
known as the "powerhouses" of the cell--from their mothers, Marianne Schwartz,
laboratory director of the department of clinical genetics at the University
Hospital Rigshospitalet in Copenhagen, Denmark, said in an interview with
Reuters Health. </font></p>
<p><font face="Arial">But Schwartz and her colleague found a man who had
inherited some of his mitochondria from his father, according to a report
published in the New England Journal of Medicine ( <a
href="http://rd.yahoo.com/dailynews/nm/hl_nm/inlinks/*http://rd.yahoo.com/DailyNews/manual/*http://search.news.yahoo.com/search/news?p=%22New%20England%20Journal%20of%20Medicine%22&c=&n=20&yn=c&c=news&cs=nw">news</a>
- <a
href="http://rd.yahoo.com/dailynews/nm/hl_nm/inlinks/*http://rd.yahoo.com/DailyNews/manual/*http://search.yahoo.com/bin/search?p=New%20England%20Journal%20of%20Medicine">web
sites</a>). </font></p>
<p><font face="Arial">The 28-year-old man came into her clinic complaining
of severe fatigue after the slightest exercise. Although his lungs and heart
were completely normal, the man had never been able to run more than a few
steps without tiring, Schwartz said. And everyone in his immediate family
was completely healthy. </font></p>
<p><font face="Arial"><a
href="http://story.news.yahoo.com/news?tmpl=story2&cid=571&ncid=571&e=10&u=/nm/20020821/hl_nm/dna_dad_dc_1">Full
text</a></font></p>
<p><font face="Arial"><font face="Trebuchet MS"><font size="5">Findings Challenge
Biological Tenet<br>
</font><font id="subhead" size="+1">Patient's disease questions solely maternal
inheritance</font><br>
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<span id="byline">By Delthia Ricks</span><br>
<span id="titleline">STAFF WRITER</span><br>
<br>
<span id="date">August 22, 2002</span><br>
<br>
</font></p>
<div id="text"><font face="Arial">In a discovery that upsets one of the central
dogmas of biology, scientists in Denmark have determined that a 28-year-old
man inherited a disease from his father that until now was believed transmissible
only through women, scientists report in a study released today.<br>
<br>
The finding zeros in on the components of cells called the mitochondria,
the main sources of the body's energy. These tiny bean-shaped constituents,
found in each cell, carry their own DNA, apart from the body's nuclear genes
inherited from both parents. Mitochondrial DNA has been believed passed
from one generation to the next only along a maternal line of inheritance.
Fathers, scientists long believed, did not transmit them. The sperm cells'
few mitochondria, scientists discovered only two years ago, are assassinated
by killer proteins in the egg. This molecular murder plot is carried out
not long after conception.<br>
<br>
Now, Dr. Marianne Schwartz and colleagues in the department of clinical
genetics at the Copenhagen Muscle Research Center have found that a man
not only has inherited paternal mitochondria, but that he has developed
a genetic muscle disease caused by a distinct defect due to paternal inheritance.<br>
</font></div>
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<pre class="moz-signature" cols="$mailwrapcol">--
M. Hubey
<a class="moz-txt-link-abbreviated" href="mailto:hubeyh@mail.montclair.edu">hubeyh@mail.montclair.edu</a> /\/\/\/\//\/\/\/\/\/\/<a class="moz-txt-link-freetext" href="http://www.csam.montclair.edu/~hubey">http://www.csam.montclair.edu/~hubey</a></pre>
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