34.2073, Books: More than words: Selten

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LINGUIST List: Vol-34-2073. Thu Jun 29 2023. ISSN: 1069 - 4875.

Subject: 34.2073, Books: More than words: Selten

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Date: 23-Jun-2023
From: Tessa Arneri [lotdissertations-fgw at uva.nl]
Subject: More than words: Selten


Title: More than words
Subtitle: the 22q11.2 deletion syndrome as a genetic model for
understanding variability in neuropsychiatric symptoms of children
with developmental language disorder
Series Title: LOT Dissertation Series
Publication Year: 2023
Publisher: Netherlands Graduate School of Linguistics / Landelijke
(LOT)
                http://www.lotpublications.nl/
Book URL: https://www.lotpublications.nl/more-than-words

Author: Iris Selten
Paperback: ISBN: 9789460934315 Pages: 240 Price: Europe EURO 36
Abstract:

Besides having persistent language difficulties, children with
Developmental Language Disorder (DLD) frequently experience symptoms
that are associated with various neuropsychiatric disorders. However,
the extent to which children with DLD develop such neuropsychiatric
symptoms is variable. A better understanding of the relationship
between early language ability and the occurrence of neuropsychiatric
symptoms, might improve our ability to identify those children with
DLD who have the highest risk to develop neuropsychiatric symptoms,
and therefore potentially most benefit from targeted intervention. One
factor that may hinder progress in understanding this relationship in
DLD, is the etiological heterogeneity that characterizes this
population, implying that the origin of DLD varies from
child-to-child. Studying a population with a homogeneous etiology
could therefore provide a unique opportunity to study the relationship
between language difficulties and co-occurring neuropsychiatric
symptoms. The central approach that was used in this dissertation was
the comparison of children with DLD to such an etiologically
homogeneous group: children with the 22q11.2 deletion syndrome
(22q11DS). Similar to DLD, 22q11DS is associated with early language
difficulties and increased prevalence rates of a variety of
neuropsychiatric symptoms. However, children with 22q11DS have a
shared etiology, being a missing piece of DNA on chromosome 22q11DS.
Results of this dissertation provide new insights on the impact of
language difficulties on the occurrence of neuropsychiatric symptoms
in 22q11DS, which might provide leads for future research and clinical
care for 22q11DS and DLD, and might also be of relevance to other
clinical populations.

Linguistic Field(s): Clinical Linguistics

Written In: English (eng)

See this book announcement on our website:
http://old.linguistlist.org/pubs/books/get-book.cfm?BookID=171913



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