[Ads-l] Relevant to the etymology of...

Wilson Gray hwgray at GMAIL.COM
Thu Jan 18 20:18:36 UTC 2018

_kick the habit_?

Or merely old news? Youneverknow.

"_Akathisia_ is a movement disorder characterized by a feeling of inner
restlessness and an inability to stay still. Usually, the legs are most
prominently affected."
. . .

"Akathisia is frequently associated with the use of
dopamine-receptor-antagonist antipsychotic drugs. Understanding is still
limited on the pathophysiology of akathisia, but it is seen to be
associated with medications which block dopaminergic transmission in the
brain.  . . .  Another major cause of the syndrome is the
withdrawal[-symptoms] observed in drug-dependent individuals. Since
dopamine deficiency (or disruptions in dopamine-signaling) appears to play
an important role in the development of [restless-leg syndrome], a form of
akathisia focused in the legs, the sudden withdrawal or rapidly-decreased
dosage of drugs which increase dopamine-signaling may create similar
deficits of the chemical which mimic dopamine-antagonism and thus can
precipitate [restless-legs syndrome]. This is why sudden cessation of
opioids, cocaine, serotonergics, and other euphoria-inducing substances
commonly produces [restless-legs syndrome] as a side-effect."


"_Restless legs syndrome_ (RLS) is a disorder that causes a strong urge to
move one's legs. . . ."
. . .

"Signs and symptoms"
. . .

"Motor restlessness, expressed as activity, which relieves the urge to

"Movement usually brings immediate relief, although temporary and partial.
 . . .  Continuous, fast, up-and-down movements of the leg, and/or rapidly
moving the legs toward, then away, from each other may keep sensations at
bay. . ."


All say, "How hard it is that we have to die!"---a strange complaint to
come from the mouths of people who have had to live.
-Mark Twain

The American Dialect Society - http://www.americandialect.org

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