Using DNA to find Goths
authurn2002
harry at CPT.CO.UK
Mon Sep 11 09:05:54 UTC 2006
--- In gothic-l at yahoogroups.com, "sturlus" <sellingvaag at ...> wrote:
> I'll be
> sure to keep everyone posted!
>
> Wish us luck!
>
> Sturla
Hi Sturla,
Yes, please do keep us posted and I do wish you luck.
One aspect I have been looking into is the Factor V Leiden mutation, a
genetic blood clotting disorder which has an interesting distribution.
It can be passed by either males or females.
FVL is thought to have a single origin in the near east between 21,000
and 34,000 years ago and is thought to have spread into europe in the
neolithic. It exists in the Lebanon, Syria, Cyprus etc at a frequency
of between 12% and 14%. In Turkey its frequency is around 9%.
Northern europe sees a gradient ranging from around 3% in the west to
around 7% in the east. Southern Sweden however has a very high
frequency of 15%, completely bucking the trend.
The gradient decreases on a north to south axis but Hungary again has
a high frequency of around 10%.
There are interesting variations in Italy and Spain too. Though the
frequencies here are much lower, around 3%, these tend to be in
pockets in the north. FVL however is virtually absent amongst the
Basques and North Africans, posing the question, who brought it into
Iberia? There doesn't appear to have been much yDNA geneflow from the
eastern mediterannean to the western mediterranean, the Balkans seem
to have been a barrier to this. I don't know if there is any mtDNA
info though.
The spread of FVL in southern sweden is quite a puzzle. It is absent
amongst saami and only exists at frequencies of around 2.5% in western
Finland.
Although it is a disorder, it does have some selective evolutionary
advantages, increased resistance to sepsis or types of blood poisoning
and lower blood loss from wounds or during childbirth.
cheers
authurn
a resident of elmet
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