Appel: workshop on Computational Methods in Pharmacovigilance

Thierry Hamon thierry.hamon at UNIV-PARIS13.FR
Fri Jun 1 19:13:15 UTC 2012

Date: Wed, 30 May 2012 15:24:03 +0200
From: marie dupuch <dupuchm at>
Message-ID: <DUB107-W209009051A5007A9C76FCBC80A0 at phx.gbl>

MIE 2012 workshop
Computational Methods in Pharmacovigilance
Pharmacovigilance is the activity related to the collection, analysis
and prevention of adverse drug reactions induced by drugs or
biologics. This activity plays the fundamental role in monitoring the
patient safety during their healthcare process and beyond it. Although
this activity relies on a strong surveillance tradition within the
pharmacoepidemiological area, some limitations appear and generate
uncomfortable cases widely covered by media (such as those related to
Mediator, VIOXX etc). First of all, these are due to the ever increasing
amount of the data to collect and to process, and also to the recording
and storage of these data in the digital form. Hence, the computational
methods may provide with useful and intelligent solutions for a more
rapid and systematic management of these data.
In this workshop, we favour the submission of various and novel
experiments related to the computational methods in pharmacovigilance and
describing different aspects of the pharmacovigilance process, as
performed by acamedic researchers, institutional or industrial people:

– Collection of the pharmacovigilance data: traditionnally, the
  pharmacovigilance cases are narrative documents spontaneously
  submitted by medical staff, by pharmacists and sometimes even by
  patients themselves.  The actual concern is that the collection of
  these cases is far from being complete. In this situation, special
  efforts are oriented on the computational assistance when collecting
  and gathering the pharmacovigilance cases from the raw textual
  sources. Moreover, the reporting standards and frames are also
  addressed by the researchers.

– Analysis of the pharmacovigilance data: this step relies on the
  encoding of the cases with the dedicated terminologies and then on the
  semantic and statistical analysis of these cases. The concerns are
  related to various aspects, such as (1) the semantic correspondence
  between the cases and the terms; (2) the methods for the encoding of
  the cases; (3) the managing of semantic ambiguity and relatedness
  between the terms; (4) exploitation of the SMQs and of the related
  data; (5) terminological and ontological representation within the
  dedicated terminologies; (6) computational methods for the signal
  detection, etc.

– Prevention of adverse drug reactions: the prevention step aims at
  facilitating the exchange of information through the well established
  national and international networks. It manages specifically the
  grave adverse drug reactions and the guidelines which help countries
  to strengthen the pharmaceutical politics and decisions.

– etc.
The objective of this workshop is to gather people working on various
aspects of the pharmacovigilance. Experiments performed within academic,
instritutional or industrial contexts are welcome.
The authors are invited to prepare 5 page submissions with the respect
of the MIE conference style:

For any questions, please contact natalia.grabar at
May 1, 2012: 1st call for submissions
June 15, 2012: Paper due date
July 10, 2012: Notifications to Authors
July 25, 2012: Camera-ready version
Aug 28, 2012: MIE conference and workshop
- Ismaïl Ahmed, Equipe Biostatistique, CESP, UMRS 1018 Inserm, Université
  Paris Sud, France
- Andrew Bate, Visiting Professor, Department of Information Systems and
  Computing, Computing and Mathematics, Brunel University, London, UK,
  Adjunct Associate Professor of Medicine, Division of Clinical
  Pharmacology NYU School of Medicine, New York, USA and faculty of the
  NYU Center for Health Informatics and Bioinformatics, USA
- Kevin Cohen, University of Colorado School of Medicine and University
  of Colorado at Boulder, USA
- Mélanie Courot, BC Cancer Agency, Vancouver, Canada
- Reinhard Fescharek, Behring Inc., Germany
- Thierry Hamon, LIM&BIO, Université Paris 13, France
- Mikaela Keller, CNRS LIFL UMR8022, Mostrare INRIA, Université Lille 1
  and 3, France
- Halil Kilicoglu, National Library of Medicine, NIH, USA
- Niklas Noren, Uppsala Monitoring Centre, WHO Collaborating Centre for
  International Drug Monitoring, Uppsala, Sweden
- Patrick Ruch, University of Applied Sciences, Geneva, Switzerland
- Ozlem Uzuner, University at Albany, SUNY, USA
- ...
Marie Dupuch, CNRS STL UMR 8163, U Lille 1 et 3, France
Frantz Thiessard, ISPED, U Bordeaux Segalen, France
Natalia Grabar, CNRS STL UMR 8163, U Lille 1 et 3, France
Jim Slattery, European Medicines Agency, London, UK

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