[language] [Fwd: [evol-psych] 'Maternal' DNA Can Be Inherited from Dad, Too]

[H.M. Hubey]

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-------- Original Message --------
Subject: [evol-psych] 'Maternal' DNA Can Be Inherited from Dad, Too
Date: Thu, 22 Aug 2002 18:01:06 -0600
From: Ian Pitchford <ian.pitchford at scientist.com>
Reply-To: Ian Pitchford <ian.pitchford at scientist.com>
Organization: http://human-nature.com/
To: evolutionary-psychology at yahoogroups.com



'Maternal' DNA Can Be Inherited from Dad, Too
Wed Aug 21, 5:43 PM ET

By Linda Carroll

NEW YORK (Reuters Health) - Tiny bits of DNA that scientists thought
could only come from a child's mother may sometimes also come from the
father, a new study shows.

Usually, mammals inherit mitochondria--small structures known as the
"powerhouses" of the cell--from their mothers, Marianne Schwartz,
laboratory director of the department of clinical genetics at the
University Hospital Rigshospitalet in Copenhagen, Denmark, said in an
interview with Reuters Health.

But Schwartz and her colleague found a man who had inherited some of his
mitochondria from his father, according to a report published in the New
England Journal of Medicine ( news
<http://rd.yahoo.com/dailynews/nm/hl_nm/inlinks/*http://rd.yahoo.com/DailyNews/manual/*http://search.news.yahoo.com/search/news?p=%22New%20England%20Journal%20of%20Medicine%22&c=&n=20&yn=c&c=news&cs=nw>
- web sites
<http://rd.yahoo.com/dailynews/nm/hl_nm/inlinks/*http://rd.yahoo.com/DailyNews/manual/*http://search.yahoo.com/bin/search?p=New%20England%20Journal%20of%20Medicine>).


The 28-year-old man came into her clinic complaining of severe fatigue
after the slightest exercise. Although his lungs and heart were
completely normal, the man had never been able to run more than a few
steps without tiring, Schwartz said. And everyone in his immediate
family was completely healthy.

Full text
<http://story.news.yahoo.com/news?tmpl=story2&cid=571&ncid=571&e=10&u=/nm/20020821/hl_nm/dna_dad_dc_1>

Findings Challenge Biological Tenet
Patient's disease questions solely maternal inheritance

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By Delthia Ricks
STAFF WRITER

August 22, 2002

In a discovery that upsets one of the central dogmas of biology,
scientists in Denmark have determined that a 28-year-old man inherited a
disease from his father that until now was believed transmissible only
through women, scientists report in a study released today.

The finding zeros in on the components of cells called the mitochondria,
the main sources of the body's energy. These tiny bean-shaped
constituents, found in each cell, carry their own DNA, apart from the
body's nuclear genes inherited from both parents. Mitochondrial DNA has
been believed passed from one generation to the next only along a
maternal line of inheritance. Fathers, scientists long believed, did not
transmit them. The sperm cells' few mitochondria, scientists discovered
only two years ago, are assassinated by killer proteins in the egg. This
molecular murder plot is carried out not long after conception.

Now, Dr. Marianne Schwartz and colleagues in the department of clinical
genetics at the Copenhagen Muscle Research Center have found that a man
not only has inherited paternal mitochondria, but that he has developed
a genetic muscle disease caused by a distinct defect due to paternal
inheritance.
Full text
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M. Hubey

hubeyh at mail.montclair.edu /\/\/\/\//\/\/\/\/\/\/http://www.csam.montclair.edu/~hubey



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